| Date | Location | Result | |
| 03-06-10 | Ypsilanti, Mich. (Convocation Center) | Eastern Michigan 66, Buffalo 56 | Box score |
| 3/2/10 | Alumni Arena (Buffalo, NY) | Kent State 67, Buffalo 55 | Box score |
| 2/27/10 | Athens, Ohio (Convocation Center) | Ohio 61, Buffalo 58 | Box score |
| 2/24/10 | Alumni Arena (Buffalo, NY) | Bowling Green 81, Buffalo 64 | Box score |
| 2/20/10 | Millett Hall, Oxford, Ohio | Miami (OH) 67, Buffalo 52 | Box score |
| 2/13/10 | Alumni Arena (Buffalo, NY) | Akron 63, Buffalo 57 | Box score |
| 2/10/10 | Ball State/Worthen Arena/Muncie, Ind. | Ball State 84, Buffalo 62 | Box score |
| 2/6/10 | Alumni Arena (Buffalo, NY) | Buffalo 60, Central Michigan 52 | Box score |
| 2/3/10 | Alumni Arena (Buffalo, NY) | Eastern Michigan 78, Buffalo 65 | Box score |
| 1/30/10 | Kalamazoo, Mich. (University Arena) | Buffalo 50, Western Michigan 46 | Box score |
| 01/27/10 | Alumni Arena (Buffalo, NY) | Toledo 69, Buffalo 67 | Box score |
| 01-23-10 | Convocation Center (DeKalb, Ill.) | Northern Illinois 93, Buffalo 88 | Box score |
| 1/19/10 | M.A.C. Center - Kent, Ohio | Kent State 68, Buffalo 66 | Box score |
| 1/16/10 | Alumni Arena (Buffalo, NY) | Buffalo 76, Ohio 62 | Box score |
| 01/13/10 | Anderson Arena; Bowling Green, Ohio | Bowling Green 78, Buffalo 60 | Box score |
| 01/09/10 | Rhodes Arena | Akron, Ohio | Akron 72, Buffalo 56 | Box score |
| 1/6/10 | Alumni Arena (Buffalo, NY) | Miami (OH) 62, Buffalo 55 | Box score |
| 1/3/2010 | Alumni Arena (Buffalo, NY) | Buffalo 64, Bucknell 51 | Box score |
| 12/29/09 | DeLand, Fla. (Edmunds Center) | Buffalo 65, Stetson 53 | Box score |
| 12/28/09 | DeLand, Fla. (Edmunds Center) | American 54, Buffalo 43 | Box score |
| 12/22/09 | Bob Carpenter Center - Newark, Del. | Delaware 85, Buffalo 72 | Box score |
| 12/13/09 | Alumni Arena (Buffalo, NY) | Buffalo 92, Youngstown State 38 | Box score |
| 12/9/09 | Reilly Center | St. Bonaventure 78, Buffalo 57 | Box score |
| 12/5/09 | Alumni Arena (Buffalo, NY) | Canisius 59, Buffalo 56 | Box score |
| 12/2/09 | Providence, R.I. (Alumni Hall) | Providence College 86, Buffalo 63 | Box score |
| 11/28/09 | Alfond Arena, Orono, Maine | Maine 58, Buffalo 53 | Box score |
| 11/27/09 | Alfond Arena, Orono, Maine | Penn State 86, Buffalo 65 | Box score |
| 11/21/09 | Alumni Arena (Buffalo, NY) | Temple 65, Buffalo 55 | Box score |
| 11/16/09 | Hempstead, NY (Mack Sports Complex) | Hofstra 77, Buffalo 60 | Box score |
| 11/13/09 | Gallagher Center | Buffalo 87, Niagara 79 | Box score |